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Most formulation scientists are drawn to complexity. Balázs Attila Kondoros was drawn to elegance. “What fascinates me is how cyclodextrins, despite their simple structure, can efficiently encapsulate molecules and solve real formulation challenges.” When asked about his proudest achievement, he does not highlight a single project. Instead, he points to a process: “Rather than one […]
CarboHyde’s Lead Formulation Expert, Balázs Attila Kondoros, will attend the Drug Delivery & Formulation (DDF) Summit in Berlin to explore advancements in drug delivery technologies. We will be investigating how cyclodextrins might address emerging formulation and delivery challenges — unlocking new possibilities for solubility, stability, and bioavailability. Kondoros plans to network with industry professionals and […]
CarboHyde, in collaboration with researchers including Salvo Sortino, Szabolcs Béni, and Milo Malanga, developed a photoresponsive β-cyclodextrin branched polymer. When exposed to visible blue light, this polymer generates nitric oxide. The researchers tested doxorubicin (DOX) in combination with the polymer. In darkness, DOX showed minimal cytotoxic effects at sub-therapeutic doses, whether used alone or combined […]
CarboHyde participated in the event organised by the Magyar Biotechnológus-hallgatók Egyesülete (Hungarian Biotechnology Students Association). Our team members Tamás Sohajda and Gergely Tóth engaged with attendees, sharing our vision and work in the cyclodextrin space. “Meeting young talents is critical to our progress and vision.” The event brought together professionals from Hungary’s biotech sector and […]
CanGoNano is a Marie Skłodowska-Curie Doctoral Network uniting European universities, research institutes, and industry partners to investigate glyconanomaterials — a rapidly advancing field combining chemistry, nanotechnology, glycobiology, and immunology. Mission The programme aims to design nanoscale systems built from carbohydrates that can interact with the immune system in highly specific ways, with applications in cancer […]
CarboHyde announces a research collaboration that has yielded a new publication. The team — including Salvo Sortino, Szabolcs Béni, and Milo Malanga — developed a photoresponsive β-cyclodextrin branched polymer. When exposed to visible blue light, the polymer generates nitric oxide. The researchers tested doxorubicin (DOX) in combination with the polymer, showing that light irradiation significantly […]
Using cyclodextrins for wound healing applications has been explored extensively, with numerous promising prototypes developed — though none have reached commercial markets until now. A breakthrough innovation by Jun Li at the National University of Singapore demonstrates a “smart multifunctional ROS-responsive supramolecular hydrogel.” This polymer is dynamically crosslinked through inclusion complexes formed between β-cyclodextrin and […]
CarboHyde’s Chief Operating Officer and Nutraceutical Innovation Head, Tamás Vargadi, will participate in the upcoming Vitafoods event in Barcelona to examine recent developments in food supplement innovations. We are particularly interested in leveraging cyclodextrins to address emerging delivery challenges — unlocking new possibilities for improved solubility, stability, and bioavailability. Vargadi will network with industry professionals, […]
Glioblastoma (GB) is the most common and aggressive malignant brain tumor, with a median survival of only 12–15 months. Emerging therapeutic approaches target the MAPK/ERK signalling pathway using MEK inhibitors such as trametinib and selumetinib. However, clinical progress faces obstacles including inadequate blood-brain barrier penetration and dose-limiting toxicity concerns. Researchers Noemi Bognanni, Graziella Vecchio, and […]
RotaChrom Technologies, a global player in Centrifugal Partition Chromatography (CPC), published research on scalable enantioseparation of rac-voriconazole. Key Innovation Batch CPC baseline intensified to cyclic continuous stacked-injection CPC MDM CPC mode enables continuous injection and dual-outlet product collection MDM CPC intensification delivers approximately 25× productivity gain versus resolution Continuous CPC reduces solvent and selector use […]
