CarboHyde announces a research collaboration that has yielded a new publication. The team — including Salvo Sortino, Szabolcs Béni, and Milo Malanga — developed a photoresponsive β-cyclodextrin branched polymer.

When exposed to visible blue light, the polymer generates nitric oxide. The researchers tested doxorubicin (DOX) in combination with the polymer, showing that light irradiation significantly enhances cytotoxicity when the drug is combined with the polymer — a result attributed to the combined action of nitric oxide.

Published as: “Phototherapeutic β-Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin” in Biomacromolecules.