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Presentation materials on cyclodextrin science and formulation development, free to download and use for educational purposes.
This slidedeck presents CarboHyde’s mission, core activities and growing role in cyclodextrin-based innovation. It highlights the company’s CRO and CDMO capabilities in synthesis, formulation and analytics, as well as its research collaborations, development pipeline and emerging cyclodextrin-based products and technologies.
DOWNLOAD PDFThis slidedeck presents CarboHyde’s analytical capabilities for cyclodextrins and their derivatives, including HPLC, NMR, mass spectrometry, CE, DLS/SLS, TGA, DSC and Karl Fischer titration. It highlights how these techniques can support identity and purity testing, impurity profiling, structural characterization, degradation studies, reaction monitoring and physicochemical analysis.
DOWNLOAD PDFThis slidedeck presents cyclodextrins as multifunctional excipients in small-molecule drug delivery, with applications ranging from solubilization and taste masking to chemical stabilization and improved dissolution. It also introduces key complexation methods and outlines a typical cyclodextrin-based formulation development workflow, from pre-formulation and phase-solubility studies to stability testing and technology transfer.
DOWNLOAD PDFThis slidedeck explains the structure and mechanism of action of cyclodextrins, the key factors influencing complex formation and dissociation, and their main benefits and limitations in drug delivery. It also introduces common formulation technologies and highlights the use of different cyclodextrins in marketed pharmaceutical products across multiple administration routes.
DOWNLOAD PDFThis slidedeck explores therapeutic cyclodextrins acting as APIs, from antidote-type applications such as sugammadex to cholesterol- and lipid-targeting approaches in rare diseases, inflammation, cancer and antiviral therapy. It also highlights next-generation cyclodextrin technologies and the key challenges ahead: understanding their mechanisms of action and designing new, purpose-built cyclodextrins.
DOWNLOAD PDFThis slidedeck shows how cyclodextrin modification can improve solubility, binding selectivity and biological functionality. Through practical examples, it highlights their use in drug reversal, photodynamic therapy, vaccine production and adjuvants, selective sequestration, cancer targeting and radiopharmaceutical imaging.
DOWNLOAD PDFThis slidedeck introduces the reactivity of cyclodextrin hydroxyl groups and the main approaches used for their chemical modification. It covers random alkylation, selective functionalization through mono-6-tosyl and per-6-halogen intermediates, advanced regioselective strategies, the synthesis of sugammadex, and routes toward functional cyclodextrin polymers.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in food and nutrition, from solubilization, flavor stabilization and taste masking to active packaging and shelf-life improvement. It also highlights applications in starchy foods, cholesterol reduction, egg-free baking, dietary supplements and other functional food concepts.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in biotechnology, including microbial and enzymatic conversions, fermentation, vaccine production and monoclonal antibody stabilization. It also highlights applications in tissue culture, analytical detection and cryoprotection, showing how cyclodextrins can improve solubility, reduce inhibition and protect biological systems.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in vaccines as stabilizers, adjuvants and cryoprotectants. It highlights examples from human and veterinary vaccines, including HPBCD- and sulfolipo-CD-based applications, and also shows how cyclodextrins can improve vaccine production by protecting sensitive components and reducing growth-inhibiting effects.
DOWNLOAD PDFThis slidedeck presents the role of cyclodextrins as multifunctional excipients in veterinary products, including oral, injectable and chewable formulations. It highlights marketed examples using HPBCD, SBEBCD and γ-CD, as well as applications in veterinary vaccines, solubilization and the development of anti-inflammatory, antibacterial and antifungal therapies.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in agriculture, from improving pesticide solubility, stability and controlled release to reducing volatility and applied dose. It also highlights applications in seed treatment, bee health, animal feed, vitamin and essential-oil delivery, fish pigmentation and other emerging uses in animal husbandry.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in nutraceuticals and dietary supplements, with examples including CoQ10, curcumin, CBD, R-α-lipoic acid, resveratrol, essential oils and vitamins. It also highlights formulation strategies for improving absorption, converting oily ingredients into powders and enabling sustained-release and other advanced dosage forms.
DOWNLOAD PDFThis slidedeck explores cyclodextrins as multifunctional excipients in peptide formulations, from direct host–guest interactions to aggregation control and absorption enhancement. It highlights approved products such as Kyprolis, Baqsimi and Egrifta WR, together with emerging applications in insulin delivery, peptide co-formulation and incompatibility reduction.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in skincare, haircare, fragrances and other cosmetic products. It highlights their roles in solubilization, stabilization, controlled release, odor masking and penetration enhancement, with practical examples including retinoids, vitamin E, ferulic acid, resveratrol and fragrance formulations.
DOWNLOAD PDFThis slidedeck explores cyclodextrin-based gene delivery platforms, including cationic polymers, amphiphilic cyclodextrins, polyrotaxanes and supramolecular systems. It highlights their ability to form and stabilize DNA, siRNA and ASO nanocomplexes, enhance cellular uptake and targeting, and support endosomal escape, while also addressing key challenges such as toxicity, synthesis complexity and clinical translation.
DOWNLOAD PDFThis slidedeck explores the use of cyclodextrins in innovative formulation platforms, including electrospun nanofibers, 3D-printed dosage forms, microneedles and micro-/nanorobots. It highlights how cyclodextrins can improve API stability, solubility and bioavailability while supporting fast-dissolving, personalized and targeted drug-delivery systems.
DOWNLOAD PDFHQ – Labs & Offices Located in the European Union – Budapest, Hungary The staff of researchers trained in carbohydrate chemistry, manufacturing, formulation, and analysis. We believe that the importance of serving patients is superior to our internal goals, thus CarboHyde team is happy to assist other companies in their cyclodextrin-related developments.