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CarboHyde announces a research collaboration that has yielded a new publication. The team — including Salvo Sortino, Szabolcs Béni, and Milo Malanga — developed a photoresponsive β-cyclodextrin branched polymer. When exposed to visible blue light, the polymer generates nitric oxide. The researchers tested doxorubicin (DOX) in combination with the polymer, showing that light irradiation significantly […]
Glioblastoma (GB) is the most common and aggressive malignant brain tumor, with a median survival of only 12–15 months. Emerging therapeutic approaches target the MAPK/ERK signalling pathway using MEK inhibitors such as trametinib and selumetinib. However, clinical progress faces obstacles including inadequate blood-brain barrier penetration and dose-limiting toxicity concerns. Researchers Noemi Bognanni, Graziella Vecchio, and […]
